ANTIULCER ACTIVITY OF 3-HYDROXYIMINO DERIVATIVES OF MINOR TRITERPENOIDS OF LICORICE ROOT

Publication date: 2022

DOI: 10.1007/s11094-022-02619-w

Abstract:

3-Hydroxyimino derivatives of minor licorice triterpenoids possessed pronounced antiulcer activity and protected rat gastric mucosa from ulceration in indomethacin and orthophen ulcer models at a dose of 50 mg/kg. 3-Hydroxyimino-11-deoxoglycyrrhetic acid was the most active antiulcerogenic substance and was superior in activity to carbenoxolone

Издатель: Springer New York Consultants Bureau

Тип: Article