Publication date: 2016

DOI: 10.1007/s10600-016-1641-4

The monoterpene glycoside paeoniflorin (PF, 1) is a unique biologically active secondary metabolite from roots of Paeonia, which are widely used in traditional Chinese medicine in combination with Glycyrrhiza uralensis roots [1–4]. The PF content in roots of Siberian wild P. anomala is 1–2%. It is easily isolated from root extract by chromatographic methods [5, 6]. PF possesses anti-inflammatory and antiarrhythmic [7], analgesic [8], hepatoprotective [9], antihyperglycemic [10], and antioxidant [11] activity, exhibits neuroprotective activity, and enhances cognitive capabilities [12, 13]. The high biological activity and poorly understood reactivity of PF make its chemical transformations a critical problem

Тип: Article