Biofunctionalization of PEO coatings on titanium implants with inorganic and organic substances

Publication date: 2020

DOI: 10.1016/j.surfcoat.2020.126486


The paper concerns a choice in the biofunctionalization of the coatings produced by plasma electrolytic oxidation: either with inorganic components by introducing Ca-, P- containing compounds into the coating (primarily hydroxyapatite), or with integrin-active organic components (primarily RGD peptides). The following coatings were analyzed: E1 – titania PEO coating, E2 – titania and Ca-, P containing PEO coating, E1 + RGD – titania PEO coating modified with integrin-active RGD (arginine-glycine-aspartic acid) tripeptide sequence anchored to the surface with a bisphosphonate linker. In terms of wear resistance, electrochemical corrosion behavior, and interaction with osteoblast-like cells, coating E1 + RGD seems to be the most promising for the titanium implants.

Издатель: Elsevier Science Publishing Company, Inc.

Тип: Article