THE ROLE OF IRON IN THE PATHOGENESIS OF LICHEN PLANUS OF ORAL MUCOSA
Publication date: 2017
Abstract:
At present, the effect of deficiency or excess of various trace elements in the body on development and flow of chronic
recurrent dermatoses, including lichen planus in oral mucosa, is studied. To study the role of iron in the pathogenesis of lichen
planus of oral mucosa, its content in blood serum and saliva was determined in patients with lichen planus of oral mucosa. In
patients with lichen planus of oral mucosa, the imbalance of iron content in serum and in oral fluid of pathological or adaptive
nature was determined, which was of some importance in the pathogenesis of the disease. The interrelation between
microelements’ content in blood serum and in oral fluid and the clinical form and severity of the disease has been traced. With
increasing severity of the clinical course, a significant decrease in the level of iron was observed mainly in the oral fluid, which
in turn might aggravate severity of lichen planus of oral mucosa.