Статья
Компьютерный анализ взаимосвязи структура – активность для иммуноактивных производных тиазоло [3,2- a ] бензимидазола
2018
Computer analysis of the structure–activity relationship and purposeful design of effective immunomodulators among thiazolo[3,2-a]benzimidazole derivatives was performed. A mathematical recognition model was formulated. Immunomodulating activity of condensed azoles was predicted (80 – 100% learning recognition). Potentially active structures were generated. Their activities were predicted. Theoretical and experimental results agreed. The tested thiazolo[3,2-a]benzimidazole derivatives exhibited the predicted activities. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Дианов, В.М., Алехин, Е.К., Тюрина, Л.А. Компьютерный анализ взаимосвязи структура – активность для иммуноактивных производных тиазоло [3,2- a ] бензимидазола. 2018; https://doi.org/10.1007/s11094-018-1814-5
Цитирование
