SEARCH FOR ANTIMICROBIAL COMPOUNDS AMONG MALEOPIMARIC-ACID DERIVATIVES

Publication date: 2019

DOI: 10.1007/s10600-019-02835-z

Abstract:

The antimicrobial and antifungal activities of maleopimaric acid (MPA) and several of its 2- and 6-derivatives were investigated. An analysis of the results showed pronounced antimicrobial activity for 2-allylmaleopimarimide and MPA N-benzylcarboxamide against test strains of Gram-negative and Gram-positive microorganisms and antifungal activity of 2-allylmaleopimarimide against lower-fungus test strain Candida albicans. New methods for producing MPA N-benzylcarboxamide and N-hydroxymaleopimarimide that increased the yields of target products were proposed.

Издатель: Springer New York Consultants Bureau

Тип: Article