Publication date: 2017

The review is devoted to the problem of aggressive behavior in neurological diseases. PubMed and Google scholar databases were reviewed using terms for search "stroke", "aggression" and "aggressive behavior". Aggressive behavior is revealed in 7-35% of patients who have had a stroke and is associated with both psychological and neurobiological factors. In particular, the development of aggressive behavior is caused by structural and functional changes in amygdala, prefrontal cortex and striatum. The trials conducted for studying the problem of aggressive behavior after stroke demonstrate heterogeneous and controversial group of clinical and pathogenetic correlates. Received data have demonstrated that usually aggressive behavior after stroke is not an independent psychopathological phenomenon, but one of the symptoms of a wide variety of post-stroke cognitive and behavioral disorders. Aggressive behavior after stroke could be related to the disorders of higher brain functions (executive functions disorder, disorders of theory of mind, empathy, misoplegia, sensory aphasia, dementia); to affective disorders (anxiety, depression, fatigue, catastrophic reaction) and personality disorders (organic pseudopsychopathies); to acute (hyperactive delirium) and chronic (delusional misidentification) psychotic disorders. Special scales as well as complex neuropsychiatric work-up are used for assessment the patients with aggressive behavior after stroke. Pharmacological and non-pharmacological methods are used to manage aggressive behavior after stroke. Aggressive behavior after stroke should be diagnosed and managed with consideration of clinical and pathogenetic aspects in every individual case.

Тип: Article

DOI: 10.18821/1560-9545-2017-22-3-142-147

УДК: 616.89-008.444.9-02:616.831-005-036.11